Sub-regional organizations and groupings, such as the Brisbane Accord Group (BAG), the Asia eHealth Information Network (AeHin), and the Pacific Civil Registrars Network (PCRN) are well-placed to promote sub-regional cooperation for the improvement of CRVS.

Several sub-regional initiatives are aligned with the Regional Action Framework, including: The Pacific Vital Statistics Action Plan (PV-SAP), which was developed to support one of the four priority areas of the Ten Year Pacific Statistics Strategy 2011-2020. The Brisbane Accord Group is supporting the implementation of the PV-SAP.

The regional strategy for strengthening the role of the health sector in improving civil registration and vital statistics in South Asia, supported by the WHO Regional Committee for South-East Asia. The regional strategy for the improvement of civil registration and vital statistics systems 2014-2019 in the Eastern Mediterranean, supported by WHO Regional Committee for the Eastern Mediterranean and other CRVS partners.